（A）學術期刊論文（Refereed Papers）

1.

Wu, S. P., Liu, C. C., Hwang, T. S., Chen, J. T., Tsai, H., “Improving the Catalytic Activity of Phenylalanine Aminotransferase of Escherichia coli by Site-Specific Mutation.,”Ann. N. Y. Acad. Sci., Vol. 864, 1998, 3, pp. 561-564..

2.

Ko, T. P., Wu, S. P., Yang, W. Z., Tsai, H., Yuan, H. S., “Crystallization and Preliminary Crystallographic Analysis of the Escherichia coli Tyrosine Aminotransferase.,”Acta. Cryst., Vol. D55, 1999, 3, pp. 1474-1477..

3.

Lee, C. L., Hsiao, H. H., Lin, C. W., Wu, S. P., Huang, S. Y., Wu, C. Y., Wang, A. H. –J., Khoo, K. H., “Strategic Shutgun Proteomics Approach for Efficient Construction of an Expression Map of Targeted Protein Families in Hepatoma Cell Lines.,”Proteomics, Vol. 3, 2003, 3, pp. 2472-2486.

4.

Wu, S. P., Hwang, T. S., Ko, T. P., Wang, A. H.-J., Tsai, H., “The Structural Interpretations of Residue Ser297 in Catalytic Efficiency of Escherichia coli Phenylalanine Aminotransferase.,”Biochim. Biophys. Acta., Vol. 1647, 2003, 3, pp. 390-394.

5.

吳思霈、蔡新、黃贊勳，「轉胺酶在胺基酸生產及生物製藥上之應用.」，化工 (中國化學工程學會期刊)，第53卷第6期，民國95年12月，162-174頁。

6.

Su-Chen Ho, Szu-Pei Wu, Shih-Min Lin, Ya-Li Tang, “Comparison of anti-glycation capacities of several herbal infusions 3 with that of green tea,”Food Chemistry, 2010, 5.

7.

Peiyuan F Hsieh, Chien-Wei Hou, Pei-Wun Yao, Szu-Pei Wu, Yu-Fen Peng, Mei-Lin Shen, Ching-Huei Lin, Ya-Yun Chao, Ming-Hong Chang, Kee-Ching Jeng, “Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation,”JOURNAL OF NEUROINFLAMMATION, Vol. 8, No. 1, 2011, 7, p. 57.

8.

Jiunn‑Nan Chu, Chiu‑Chung Young, Chen‑Chung Tan, Szu‑Pei Wu, Li-Sen Young, “Improvement of productivity and polysaccharide‑protein complex in Agaricus blazei,”PESQUISA AGROPECUARIA BRASILEIRA, Vol. 47, No. 1, 2012, 1, pp. 96-102.

（B）研討會論文（Conference Papers）

1.

Wu, S. P., Liu, C. C., Hwang, T. S., Chen, J. T., Tsai, H., “Improving the Catalytic Activity of Phenylalnine Aminotrasferase of Escherichia coli by Site-Specific Mutation.,”Enzyme Engineering XIV, HI, Beijing, China, 1997, 10, 16－1997, 10, 19.

2.

Hwang, T. S., Wu, S. P., Tsai, H., “Cloning and Expression of D-Amino Acid Aminotransferase from Bacillus sphaericus in Escherichia coli.,”第十三屆生物醫學聯合學術年會, NTU, Taipei, Taiwan, 1998, 3, 16－1998, 3, 17.

3.

Wu, S. P., Hwang, T. S., Ko, T. P., Liu, C. C., Tsai, H., “Improvement of the Catalytic Activity of Phenylalanine Amintransferase of Escherichia coli : The Effects of Substitution of a Threonyl Residue for Isoleucine 17,”第十五屆生物醫學聯合學術年會, NTU, Taipei, Taiwan, 2000, 5, 16－2000, 5, 17.

4.

Hwang, T. S., Wu, S. P., Tsai, H., “A New Process for Conversion of CephC to GL-7ACA by Enzymic Transamination and Oxidative Decarboxylation,”The 11th International Biotechnology Symposium and Exhibition－Biotechnology 2000, UCC, Berlin, Germany, 2000, 9, 16－2000, 9, 19.

5.

Wu, S. P., Hwang, T. S., Ko, T. P., Tsai, H., “The Serine-297 of Escherichia coli Phenylalanine Aminotransferase is Crucial for Catalytic Efficiency.,”Enzyme Engineering XVI, U. Potsdam, Potsdam, Germany, 2001, 9, 16－2001, 9, 19.

6.

Hwang, T. S., Wu, S. P., Tsai, H., “The Upstream Sequence of Bacillus sphaericus D-Amino Acid Aminotransferase Gene Acts as Prokaryotic Enhancer on the Gene Expression in Escherichia coli.,”3rd International Symposium on Vitamin B6, PQQ, Carbonyl Catalysis and Quinoproteins, U. Southampton, Southampton, UK, 2002, 4, 14－2002, 4, 19.

7.

Wu, S. P., Juei, Y. S, Cheng, K. Y., Tsai, H., Hwang, T. S., “A New Chemo-Enzymatic Conversion Process of Cephalosporin C (Ceph C) and Homophenylpyruvate to Produce D-homophenylalanine and Glutaryl-7-aminocephalosporanic Acid (GL-7ACA) Simultaneously,”12th International Symposium of Young Asia Biochemical Engineer's Community, I-Shou University, Kaohsiung, Taiwan, 2006, 11, 25－2006, 11, 27.

8.

Hwang, T. S., Jing-Chun Ko, Yi-Chu Chang, Szu-Pei Wu, Chih-Hao Lin, Wen-Chang Chang, “Biosynthesis of L-homophenylalanine by Branched-chain Amino Acid Aminotransferase (BCAT) from Extremephilic Bacteria,”12th International Symposium of Young Asia Biochemical Engineer's Community, I-Shou University, Kaohsiung, Taiwan, 2006, 11, 25－2006, 11, 27.

9.

Hwang, T. S., Wu, S. P., Hsu, Y. T., Chen, M. Y., Tsai, S. S., Chang, W. C., “Characterization and Application of Aspartate Aminotransferase (AspAT) from Radiation-Resistant Bacterium Deinococcus radiodurans R1.,”12th International Symposium of Young Asia Biochemical Engineer's Community, I-Shou University, Kaohsiung, Taiwan, 2006, 11, 25－2006, 11, 27.

10.

Chang, Y. C., Ko, J. C., Wu, S. P., Lin, C. H., Chang, W. C., Hwang, T. S., “Cloning, Expression and Characterization of Branched-Chain Amino Acid Aminotransferase (BCAT) From Thermus thermophilus HB8,”第22屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2007, 3, 24－2007, 3, 25.

11.

Cheng, W. C., Fu, H. C., Wu, S. P., Chang, W. C., Hwang, T. S., “Aspartate Aminotransferase (AspAT) From Thermophilic Bacterium Thermus thermophilus HB8,”第22屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2007, 3, 24－2007, 3, 25.

12.

Wu, S. P., Hwang, T. S., Tsai, H., “Direct Evolution of Phenylalanine Aminotransferase for Improving the Catalytic Activity Against Phenylalanine and Homophenylalanine,”13th European Congress on Biotechnology J. Biotechnology, Vol. 131,Fira, Barcelona, Spain, 2007, 9, 16－2007, 9, 19.

13.

Hwang, T. S., Wu, S. P., Chen, K. Yo., Chen, K. Y., Lin, C. H., Chang, W. C., “Branched-Chain Amino Acid Aminotransferase (BCATs) from Extremephilic Bacteria and Their Pharmaceutical Application,”13th European Congress on Biotechnology J. Biotechnology, Vol. 131,Fira, Barcelona, Spain, 2007, 9, 16－2007, 9, 19.

14.

Wu, P. H., Hwang, T. S., Wu, S. P., “High-throughput Screening Mutants of D-Amino Acid Aminotransferase (DAT), Phenylalanine Aminotransferase (PheAT), and D-Amino Acid Oxidase (DAO) in Escherichia coli by a Replica-paper Staining Method,”第23屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2008, 3, 29－2008, 3, 30.

15.

Cheng, K. Y., Wu, S. P., Hwang, T. S., “Biosynthesis of L-tert-Leucine and L-Homophenylalanine by Thermus thermophilus HB8 Branched-chain Amino Acid Aminotransferase (TtBCAT),”第23屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2008, 3, 29－2008, 3, 30.

16.

Kao, W. J., Wu, S. P., Lin, C. H., Chang, W. C., Hwang, T. S., “Characterization and Application of Deinococcus radiodurans Branched-chain Amino Acid Aminotransferase (DrBCAT),”第23屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2008, 3, 29－2008, 3, 30.

17.

Hwang, T. S., Kao, W. J., Wu, S. P., “Cloning And Structural Characterization Of Gluconobacter Oxydans Cephalexin-Synthesizing Enzyme,”The 33rd FEBS Congress and 11th IUBMB Conference, Megaron Athens International Conference Center, Athens, Greece, 2008, 6, 28－2008, 7, 3.

18.

Hwang, T. S., Chen, G. J., Wu, S. P., Lin, C. H., Chang, C. W., “Cloning and Characterization of Thermus thermophilus Branched-Chain Amino Acid Aminotransferase,”The Second International Interdisciplinary Conference on Vitamins, Coenzymes, and Biofactors, Athens, Georgia, USA, 2008, 10, 26－2008, 10, 30.

19.

Chen, G. J., Wu, S. P., Fu, H. C., Lin, L. L., Hwang, T. S., “Properties of Thermus thermuphilus Aspartate Aminotransferase in Biosynthesizing Homophenylalanine,”The Second International Interdisciplinary Conference on Vitamins, Coenzymes, and Biofactors, Athens, Georgia, USA, 2008, 10, 26－2008, 10, 30.

20.

Chen. G. Y., Hwang, T. S., Wu, S. P., “Enzymatic Biosynthesis of Branched-Chain Amino Acids for Nutritional Additive and Medicinal Use,”2008年健康與管理學術研討會, 元培, 新竹, 台灣, 2008, 12, 20－2008, 12, 20.

21.

Szu-Han Chou, Je-Wen Juang, Je-Wen Juang, Li-Wen Fang, Szu-Pei Wu, Tzann-Shun Hwang, “Molecular Cloning, Expression and Characterization of Malate Dehydrogenease from the Thermophilic Bacterium Thermus thermophilus HB8,”第24屆生物醫學聯合學術年會, 國防, Taipei, Taiwan, 2009, 3, 21－2009, 3, 22.

22.

Yu-Xiang Jiang, Tzann-Shun Hwang, Szu-Pei Wu, “High-throuhhput screening of phosphatase in Escherichia coli by a replica-paper staining method,”2009台灣藥學會藥物化學研討會 , 溪頭, 南投, Taiwan, 2009, 6, 28－2009, 6, 30.

23.

Szu-Pei Wu, Szu-Han Chou, Chun-Hua Hsu, Tzann-Shun Hwang, “Structural Interpretation of Thermo-Biochemical Properties and Thermostability of Malate Dehydrogenase From Thermus thermophilus HB8,”The 34th FEBS Congress, Prague, Prague, Czech Republic, 2009, 7, 4－2009, 7, 9.

24.

羅慧如、吳思霈、沈賜川、黃贊勳，「豆漿與豆漿優格中a-半乳糖寡糖含量之分析與探討」，首屆海兩岸高校保健營養學專業教學科研學術研討會，福州：福建生物工程職業技術學院，民國99年4月23日－民國99年4月26日，253頁。

25.

Szu-Pei Wu, Hui-Ru Luo, Tzann-Shun Hwang, “Thermal Biosynthesis of Homophenylalanine by Thermus thermophilus aspartate aminotransferase,”The 35th FEBS Congress , Gothenburg, Gothenburg, Sweden, 2010, 6, 26－2010, 7, 1, p. 237.

26.

侯建維, 林毓姿, 姚佩雯, 吳思霈, 莊路德, “Sesamin protects PC12 cells from kainic acid injury by inhibition of ERK expression,”台灣食品科學技術學會第14屆會員大會, 中興大學, 台中, 台灣, 2010, 12, 3－2010, 12, 3.

27.

Szu-Pei Wu, Wan-Jung Kao, Chih-Hao Lin, Wen-Chang Chang, Tzann-Shun Hwang, “Characterization and Pharmacertical Application of Branched-Chain Amino Acid Aminotransferase (BCAT) From Deinococcus radiodurans,”International Conference on Cofactors 03, Turku, Turku, Finland, 2011, 7, 10－2011, 7, 15, p. 49.

（D）專利 (Patents)

1.

A Novel D-Amino Acid Aminotransferase for Simultaneously Producing Glutaryl-7-aminocephalosporamic Acid and D-Amino Acid., U. S., 6,337,190., Hwang, T. S., Wu, S., Development Center for Biotechnology, Invention Patent, No, Certifying, 2000, 1, 1－2018, 12, 31.

2.

同時產製戊二醯基-7-胺基頭孢菌素酸及D-胺基酸之新穎D-胺基酸轉胺酶，中華民國專利，541315，黃贊勳 ;吳思霈 ;周欣樺 ;陳華儀，財團法人生物技術開發中心，發明專利，無，已核准，民國89年1月1日－民國107年12月31日。

3.

合成芳香族胺基酸之方法，中華民國，TW201102432A1，黃贊勳, 鄭瑋駿, 傅慧娟, 吳思霈，義守大學，發明專利，無，已核准，民國98年07月03日－民國108年07月03日。

4.

Synthesis Method of Aromatic Amino Acid, United States, 8,183,016 B2, Wu Szu-Pei, Hwang T., I-shou University, Invention Patent, No, Certifying, 2010, 2, 17－2020, 2, 17.

（E）參與主持的政府機構研究計畫（Chairman of Government Sponsored Research Project）

1.

台灣嗜熱性溫泉菌之具生物產業的高活性熱穩定酵素的研究開發與應用（97-2313-B-264-003-MY3），國科會，2008/08－2011/07。

2.

國科會50科學之旅:新興科技－生物科技知性之旅（97-2515-S-264-001-），國科會，2008/08－2009/12。