周育緯
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姓名 |
周育緯 |
職稱 |
助理教授 |
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電話 |
03-5381183#8150 |
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辦公室位置 |
H505-1 |
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信箱 |
ywchou@mail.ypu.edu.tw |
學 歷 ╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴
高雄醫學大學 藥學系 博士
高雄醫學大學 藥學系 碩士
高雄醫學大學 藥學系 學士
經 歷 ╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴
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服務機關 |
部門/系所 |
職稱 |
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現職 |
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元培醫事科技大學 |
生物科技暨製藥技術系 |
助理教授 |
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經歷 |
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國家科學及技術委員會 |
科技辦公室 |
副研究員 |
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中華景康藥學基金會 |
健康大數據永續平台專案辦公室(衛福部委辦) |
副研究員 |
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生物技術開發中心 |
生醫商品化中心 |
研究員/資深經理 |
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永齡健康基金會 |
生醫資訊研發專案 |
資深專案經理 |
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高雄長庚紀念醫院 |
醫學研究部 |
臨床助理研究員 |
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組織銀行核心實驗室 |
博士級管理員 |
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人體生物資料庫 |
生醫組長 |
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國立高雄科技大學 |
通識中心 |
兼任助理教授 |
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高雄醫學大學附設醫院 |
肝膽腸胃科 |
博士後研究員 |
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美國內布拉斯加州立大學醫學中心 |
生化暨分子生物系 |
博士後研究員 |
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高雄醫學大學 |
藥學系 |
博士後研究員 |
研究領域 ╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴
Biopharm、癌症生理、藥物微量分析
獎勵與榮耀 ╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴
國立高雄科技大學 教學成效績優教師
第76屆日本癌症學會Travel Grant Award
學術成果 ╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴╴
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期刊發表 |
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1. |
精準健康資料建置運用模式 王俞佳，周育緯，黃靜淑，廖益偉，謝逸慧 當代醫藥法規月刊 158(2023)1-18。 |
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2. |
Dynamics of antioxidant heme oxygenase-1 and pro-oxidant p66Shc in promoting advanced prostate cancer progression Dannah R. Miller, Matthew A. Ingersoll, Yu-Wei Chou, Elizabeth A. Kosmacek, Rebecca E. Oberley-Deegan, Ming-Fong Lin Free Radical Biology 193(2022)274-291. |
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3 |
A pilot study examining the relationship between environmental contaminants and colorectal cancer at a single medical institute in Taiwan Tian-Huei Chu*, Yu-Wei Chou*, Sheng-Lun Lin, Su-Fan Lin, Hong-Hwa Chen, Wan-Hsiang Hu, Yen-Yang Chen, Guo-Ping Chang-Chien, Jyun-Huan Chang, Meng-Chi Tsai, Chao-Cheng Huang 台灣衛誌 TJPH 40(2021)382-393. |
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Non-mitotic effect of albendazole triggers apoptosis of human leukemia cells via SIRT3/ROS/p38 MAPK/TTP axis-mediated TNF-α upregulation Liang-Jun Wang, Yuan-Chin Lee, Chia-Hui Huang, Yi-Jun Shi, Ying-Jung Chen, Sung-Nan Pei, Yu-Wei Chou*, Long-Sen Chang* Biochemical Pharmacology 162(2019) 154-168. |
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p66Shc regulates migration of castration-resistant prostate cancer cells M.A. Ingersoll, YW Chou, J.S. Lin, TC Yuan, D.R. Miller, Y. Xie, YP Tu, R.E. Oberley-Degan, S.K Batra, M-F Lin Cellular Signalling 46(2018)1-14. |
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Anti-androgen Abiraterone Acetate Improves the Therapeutic Efficacy of Statins on Castration-Resistant Prostate Cancer Cells. D.R. Miller, M.A. Ingersoll, YW Chou, B. Wakefield, YP Tu, FF Lin, W.G. Chaney, M-F Lin J Oncol Res Ther. 2017; 3(5)139. |
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Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular Carcinoma K.T. Huang, I.Y. Kuo, M.C. Tsai, C. H. Wu, L. W. Hsu, L.Y. Chen, C.P. Kung, Y.F. Cheng, S. Goto, Y.W. Chou, C. L. Chen, C.C. Lin, K.D. Chen Molecular Therapy: Nucleic Acids 9(2017)274-283. |
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Heteronemin is a Novel c-Met/STAT3 Inhibitor Against Advanced Prostate Cancer Cells Wu JC, Wang CT, Hung HC, Wu WJ, Wu DC, Chang MC, Sung PJ, Chou YW, Wen ZH, Tai MH the PROSTATE. 2016, 76(16):1469-1483. |
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Cellular prostatic acid phosphatase (cPAcP) serves as a useful biomarker of histone deacetylase (HDAC) inhibitors in prostate cancer cell growth suppression Yu-Wei Chou*, Fen-Fen Lin, Sakthivel Muniyan, Frank C. Lin, Ching-Shih Chen, Jue Wang, Chao-Cheng Huang, Ming-Fong Lin * *co-corresponding author, Cell & Bioscience 2015, 5:38. |
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Discovery of Novel N-Alkyl 4-Anilinofuro[2,3-b]Quinoline Derivatives (CIL-102 Derivatives) Against Castration-Resistant Human Prostate Cancers Lo WF, Chou YW, Tseng CH, Shiu YH, Chen YW, Yang SC, Chen YL, Lin MF, Tzeng CC Anticancer Agents Med Chem. 2015, 15(4):193-500. |
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Antiproliferative activity of novel imidazopyrudune derivatives in castration-resistant human prostate cancer cells Muniyan S, Chou YW, Ingersoll MA, Devine A, Morris M, Odero-Marah VA, Khan SA, Chaney WG, Bu XR, Lin MF Cancer Lett. 2014, 353(1):59-67. |
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p66Shc longevity protein regulates the proliferation of human ovarian cancer cells Sakthivel Muniyan*, Yu-Wei Chou*, Tiffany Tsai, Paul Thomes, Suresh Veeramani, Benedict B. Benigno, L. DeEtte Walker, John F. McDonald, Fen-Fen Lin, Subodh M Lele, Ming-Fong Lin *Equal contribution, Mol Carcinog. 2015, 54(8):618-31. |
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Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways Yu-Wei Chou*, Li Zhang*, Sakthivel Muniyan, Humera Ahmad, Satyendra Kumar, Syed Mahfuzul Alam, Ming-Fong Lin *Equal contribution, PLOS ONE 2013, 8(4), e61934. |
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Pharmacophore‐based virtual screening biological evaluation of small molecular inhibitors for protein arginine methylation Juxian Wang, Limin Chen, Sarmistha Halder Sinha, Zhongjie Liang, Huifang Cai, Sakthivel Muniyan, YuWei Chou, Chao Yang, Leilei Yan, You feng, Keqin Li, Ming‐Fong Lin, Hualiang Jiang, Yujun George Zheng, Cheng Luo J. Med. Chem. 2012, 55, 7978−7987. |
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Reactive oxygen species (ROS) by p66Shc longevity protein mediate non-genomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells Suresh Veeramani*, Yu-Wei Chou*, Frank C. Lin, Sakthivel Muniyan, Fen-Fen Lin, Satyendra Kumar, Yan Xie, Subodh M Lele, Yaping Tu, Ming-Fong Lin *Equal contribution, Free Radical Biology and Medicine 2012; 53: 95-108. |
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Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells Yu-Wei Chou, Nagendra K. Chaturvedi, Shougiang Ouyang, Fen-Fen Lin, Dharam Kaushik, Jue Wang, Isaac Kim and Ming-Fong Lin Cancer letters 2011; 311: 177-186. |
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Enantioseparation of cetirizine by sulfated-beta-cyclodextrin-mediated capillary electrophoresis. Chou YW, Huang WS, Ko CC, Chen SH. J Sep Sci. 2008; 31(5): 845-852. |
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Quantification of meropenem in plasma and cerebrospinal fluid by micellar electrokinetic capillary chromatography and application in bacterial meningitis patients. Chou YW, Yang YH, Chen JH, Kuo CC, Chen SH. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):294-301. |
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19 |
Analysis of kanamycin A in human plasma and in oral dosage form by derivatization with 1-naphthyl isothiocyanate and high-performance liquid chromatography. Chen SH, Liang YC, Chou YW. J Sep Sci. 2006; 29(5): 607-612. |
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Simultaneous determination of cefepime and L-arginine by micellar electrokinetic chromatography and applications to commercial injections. Chen YR, Lin SJ, Chou YW, Wu HL, Chen SH. J Sep Sci. 2005; 28(16): 2173-2179. |
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Trace analysis of zotepine and its active metabolite in plasma by capillary electrophoresis with solid phase extraction and head-column field-amplified sample stacking. Chou YW, Huang WS, Chen CC, Lin SJ, Wu HL, Chen SH. J Chromatogr A. 2005; 1087(1-2): 189-196. |
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Determination of ceftazidime in plasma and cerebrospinal fluid by micellar electrokinetic chromatography with direct sample injection. Yeh HH, Yang YH, Chou YW, Ko JY, Chou CA, Chen SH. Electrophoresis. 2005; 26(4-5): 927-934. |
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Book Chapters |
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1 |
Statins Enhances Anti-Androgen Abiraterone Acetate Therapeutic Efficacy on Castration-Resistant Prostate Cancer Cells Dannah R. Miller, Matthew A. Ingersoll, Yu-Wei Chou and Ming-Fong Lin New Horizons in Medicine and Medical Research Vol. 2, chapter 10, 2022. |
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Cellular Prostatic Acid Phosphatase (cPAcP) Serves as a Useful Biomarker of Histone Deacetylase (HDAC) Inhibitors in Prostate Cancer Cell Growth Suppression Yu-Wei Chou*, Fen-Fen Lin, Sakthivel Muniyan, Frank C. Lin, Ching-Shih Chen, Jue Wang, Chao-Cheng Huang, Ming-Fong Lin * Top 10 Contributions on Cell Biology, chapter 03, 2019. |
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Human Prostatic Acid Phosphatase in Prostate Carcinogenesis. Sakthivel Muniyan, Yu-Wei Chou, Shou-QiangOu-Yang, and Ming-Fong Lin Prostate Cancer: Biochemistry, Molecular Biology and Genetics; Protein Reviews, vol 16, chapter 12, 2013. |
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Research Projects |
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評估以DLK1作為漿液性卵巢癌預後與化療抗性的生物標記，MOST，20180801-20210731 (co-PI). |
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To investigate the pathophysiological function of low-density lipopreotein receptor and cholesterol bioflux in ovarian cancer development, Kaohsiung CGMH, 20180201-20190131 (PI). |
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The mechanism of benzimidazole anthelmintic drugs-induced death of leukemia cells via non-mitotic signaling pathway, Kaohsiung CGMH, 20170701-20180630 (PI). |
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The study of new pathogenic mechanism of p66Shc through EZH2 in hepatocellular carcinoma, MOST, 20170101-20180228 (PI). |
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To investigate the relationship between environmental emerging contaminants and colon cancer, Kaohsiung CGMH, 20170101-20171231(co-PI). |
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第二型人類表皮生長因子接受體(HER2)即時定量檢驗之臨床性能驗證計畫-國內多中心驗證，廠商臨床試驗計畫，20160830-20170831(co-PI) |
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To investigate the expression and drug resistance of a transcription factor CEBPD in ovarian cancer, Kaohsiung CGMH, 20150301-20160229(co-PI). |
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To investigate the expression and significance of an adaptor protein p66Shc in hepatocellular carcinoma, Kaohsiung CGMH, 20140901-20170331(PI). |
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Functional study of exosomes in oral squamous cell carcinomas, Kaohsiung CGMH, 20141001-20170930(co-PI). |
